There's a reason that Manga Studio comes chock full of tools for you to use; it's to help you streamline your work and increase your productivity. It's also nice to use a program that you don't have to necessarily shoehorn into working for you.
I happen to like this program because I get to use real-world tools on a digital plane. Sure, Photoshop and Painter have line and curve tools, but they can't create rulers and guides on the fly and treat them like the real thing! Add to that the myriad of pens, pencils, airbrushes, and screen tones (and a large number of each type of tool) that Manga Studio places at your disposal.
For EX users, it's even better, with tools like the perspective, speed, and focus line tools. Being able to set up vanishing points on the fly and just draw away like you're drawing normally is a very satisfying feeling.
There are also the various filters you can use, such as the speed and focus line filters to automatically generate lines you'd be spending time drawing by hand. Even taking advantage of the fill tool to quickly fill in large black areas shaves minutes off of your production time.
It never hurts to take advantage of the fact that this is a computer program you're working with. If there are ways that Manga Studio can save you time and headaches, by all means, use them!
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